NG2+ Glial Cells: A Novel Glial Cell Population in the Adult Brain

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Physiological characteristics of NG2-expressing glial cells.

Antibodies against the chondroitin sulfate proteoglycan NG2 label a subpopulation of glial cells within the CNS, which have a small cell body and thin radiating processes. Physiological recordings from these small cells in acute brain slices have revealed that they possess unique properties, suggesting that they may comprise a class of glial cells distinct from astrocytes, oligodendrocytes, or ...

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p10: reactive glial cells for brain injury

a common pathological process that occurred after brain injury is gliosis. gliosis involves the activation of glial cells to proliferate and become hypertrophic to occupy the injured brain areas. in order to form a defense system against the invasion of micro-organisms and cytotoxins into surrounding tissue, glial cells including astrocytes and microglia undergo reactive response to injury. neu...

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NG2 glial cells provide a favorable substrate for growing axons.

NG2 cells (polydendrocytes) comprise an abundant glial population that is widely and uniformly distributed throughout the developing and mature CNS and are identified by the expression of the NG2 proteoglycan at the cell surface. Although recent electrophysiological studies suggest that they are capable of receiving signals from axon terminals, other studies, based on the finding that the NG2 m...

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Electroconvulsive seizures induce proliferation of NG2-expressing glial cells in adult rat amygdala.

BACKGROUND Volumetric changes and glial pathology have been reported in the amygdala in patients with major depressive disorder. Here we report an analysis of glial cell proliferation in response to electroconvulsive seizures (ECS), clinically used for the treatment of severe depression. METHODS Male Wistar rats were subjected to five ECS-treatments and then injected with bromodeoxyuridine (B...

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ژورنال

عنوان ژورنال: Journal of Neuropathology and Experimental Neurology

سال: 1999

ISSN: 0022-3069

DOI: 10.1097/00005072-199911000-00001